817. Say It Ain't So by Weezer (1995)

Rivers Cuomo wrote all the music, but only had the line "Say it ain't so." The rest came when he thought of a high school moment. He came home, opened the fridge, and saw a solitary bottle of beer. His parents divorced because of his father's alcoholism. He saw the beer and worried his mother and step-father would then get divorced.

http://www.youtube.com/watch?v=ENXvZ9YRjbo